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microRNA Research Design: Strategies from the Experts
Event Date: November 10, 2009 12 noon Eastern, 9 a.m. Pacific, 5 p.m. GMT
Brought to you by the Science/AAAS Business Office
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Real Player | | | Real Media Video (56k/150k) | | |
Windows Media Player | | | Windows Media Video (56k/150k) |
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MicroRNAs, or miRNAs, are increasingly being accepted as playing a crucial regulatory role in normal and dysfunctional cellular processes. They represent a class of small, noncoding RNA molecules, which have been shown to be involved in almost every human pathology currently under study. From tumor progression and viral host interactions, to immune response and stem cell fate determination, miRNAs are quickly growing in importance as the "master regulators" in cell cycle processes. With a wide variety of research tools and potential workflows available, it can be difficult for scientists to determine the optimal path to a successful miRNA research project. This webinar will bring together three recognized experts in miRNA research and experimental design to share their knowledge and expertise.
Viewers of the webinar will:
- receive advice on best practices for establishing and running an miRNA research project
- obtain guidance on how to kick-start stalled projects
- hear solutions to common problems encountered in miRNA experiments
- be able to put their specific questions to the panelists live!
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Speakers:
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Peter T. Nelson, M.D. Ph.D.
University of Kentucky
Lexington, KY
Dr. Peter Nelson obtained his undergraduate degree in biology and economics from Rice University in Houston, Texas, followed by a joint M.D. and Ph.D. at the University of Chicago. His Ph.D. work, in Dr. Clifford Saper’s laboratory, looked at animal models of Alzheimer’s disease. After completing his medical residency and clinical fellowship training at the University of Pennsylvania, Dr. Nelson worked as a postdoctoral fellow and Research Associate in Dr. Zissimos Mourelatos’s lab, studying miRNAs. In 2006, Dr. Nelson moved to the University of Kentucky, where he is currently an associate professor in the Department of Pathology and Laboratory Medicine. He runs a laboratory in the Sanders-Brown Center on Aging and serves as an attending physician in neuropathology. Dr. Nelson is an associate editor for the Journal of Alzheimer’s Disease, a member of ACTA Neuropathologica’s editorial board (starting 2010) and has both reviewed for and published in a broad range of international, peer-reviewed journals. He invented new techniques to analyze and manipulate miRNAs, and his current research interests involve studying how miRNA biology is altered in neurodegenerative diseases, in order to better understand pathogenesis and to obtain clues relevant to potential therapies. |
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Kai Wang, Ph.D.
Institute for Systems Biology
Seattle, WA
Dr. Kai Wang completed his undergraduate training in Taiwan before moving to the United States to study for his Ph.D. at Oregon State University. Following an assistant professorship at the University of Washington in Seattle, Dr. Wang moved to industry and in 2001 co-founded PhenoGenomics Corporation. In 2008, he took a senior research scientist position at the Institute for Systems Biology in Seattle, Washington, where he currently conducts research into the application and biological function of microRNAs. Besides his over 20 years of experience as a molecular biologist in academia and industry Dr. Wang is also a diplomate of the American Board of Toxicology and is named on three US patents. |
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Neil Kubica, Ph.D.
Harvard Medical School
Boston, MA
Dr. Neil Kubica completed his undergraduate degree in biology at James Madison University in Virginia. Next, he pursued his graduate training at The Pennsylvania State University, first at the University Park main campus and then at the College of Medicine in Hershey. Dr. Kubica then joined the laboratory of Dr. John Blenis as an American Cancer Society postdoctoral fellow in the Department of Cell Biology at Harvard Medical School. The focus of his research program is on the reciprocal relationship between the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) cell signaling pathway and microRNAs in models of human cancer. Dr. Kubica has co-founded several organizations related to miRNA research including the New England RNA Data (NERD) Club (www.newenglandrna.org). The mission of the NERD Club is to allow for the dissemination of recent developments in RNA biology and to facilitate interactions between academic and industry scientists in the field. More recently, Dr. Kubica co-founded the miRNA Screeners Consortium at the Institute for Chemistry and Cell Biology-Longwood. This group of academic laboratories and industry partners established high-throughput miRNA functional screening capabilities at Harvard Medical School.
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Moderator: Sean Sanders, Ph.D., Commercial Editor, Science/AAAS
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Sean Sanders did his undergraduate training at the University of Cape Town, South Africa, and his Ph.D. at the University of Cambridge, UK, supported by the Wellcome Trust. Following postdoctoral training at the National Institutes of Health and Georgetown University, Dr. Sanders joined TranXenoGen, a startup biotechnology company in Massachusetts working on avian transgenics. Pursuing his parallel passion for writing and editing, Dr. Sanders joined BioTechniques as an editor, before joining Science/AAAS in 2006. Currently Dr. Sanders is the Worldwide Commercial Editor for the journal Science and Program Director for Outreach.
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___________________________________________________________________________________________________
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For the best experience we recommend you use Internet Explorer 6 (IE6) or higher on a Windows-based PC to view this webinar. Please ensure that you are using a computer with a stable internet connection and good bandwidth. To ensure the best possible performance of the webinar we recommend that you avoid using a dial-up connection. Note: please confirm the start time of the webinar in your time zone. A free time zone converter is available at www.timeanddate.com/worldclock/converter.html
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